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Does every person with ANA Factor positive have lupus?

No. Lupus is a disease of exclusion. You exclude other diseases by running tests and complimentary tests to those tests, until basically the only thing that remains is Lupus as the disease, even then it is not 100%. There is NO ONE definitive test for Lupus, sadly. There is a test for skin Lupus as a biopsy can be done on skin lesions. If lesions test positive for skin Lupus then you have an answer for skin Lupus.

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