80% or so of persons with lupus will experience at least episodes of joint and muscle aches, referred to as arthralgia and myalgia, during the course of their illness. Thanksfully, only about 25% develop frank inflammation in their joints which then has the possibility of producing joint deformity, so called Jaccoud"s arthropathy. Regardless, treatment with the class of medications known as antimalarials, such as plaquenil/hydorxychloroquine can provide relief. For the cases where arthritis is more persistent treatment with methotrexate, leflunomide/arava, azathioprine/imuran or cellsept/mycophenolate mofetil may be considered.
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